Nephrotic Syndrome in Cats

Nephrotic syndrome in cats can cause edema in yourkidneys where they allow for a certain amount of
pet which is fluid in their abdominal cavity, or it canboth water and waste products to leave their blood
also cause acute dyspnea, which is a difficulty inwhere it is eventually passed from their body and
breathing that can lead to panting. Panting in cats isthan through the urine. Under normal circumstances,
very unusual and is almost always a warning sign thatproteins are protected by what is called the
something is very wrong with your pet.glomerular filter.
However, this syndrome can also very rapidly causeHowever, when this filter malfunctions or becomes
your cat to loss their vision as well as kidney failure.defective, it allows for large amounts of protein to
Nephrotic syndrome in cats is a series of symptomsleave the blood circulation, passing it through their
that is caused by a combination of protein in yoururine. It is widely held that a deposition of immune
pets urine and as result of this, low protein levels incomplexes triggers an inflammatory action in your
the body. It also may produce very high andcats immune system that damages the gomeruli.
dangerous cholesterol levels as well as large levels ofOnce this occurs, it causes protenuria, which is the
fluid accumulation in their bodies.loss of protein through the urine.
There are two major causes of this very seriousIf this is left untreated, it can very rapidly cause
syndrome in your cat; Glomerulonephritis, which iskidney failure in your cat.
also referred to as GN, and Amyloidosis. Both ofThe second potential cause is from Amyloidosis,
these underlying conditions are hereditary or familiar,which is a disorder of protein metabolism where an
meaning that it will affect several members of theabnormal amount of deposits of protein referred to
same litter or the same family. It can also beas amyloid are deposited into your cats kidneys. The
acquired, meaning that your cat may develop it asactual reason for this happening is still not known at
they get older, but is not nearly as common.this time, but it is believed to be some type of
This syndrome can attack any cat at any age, ashereditary problem that affects predominately Asian
well as any breed. However, it does seem to bebreeds, especially the Abyssinian breed.
more common in middle aged and older casts as wellHowever, it can also affect mixed breeds and occurs
as favoring Asian breeds of cats, especially if themuch more commonly in older females, and the
underlying cause is Amyloidosis.deposits of protein in the kidneys leads to chronic
Symptoms:kidney failure if it is not treated. It can, however,
There are several very distinct symptoms with thisspread and affect other organs such as the liver,
syndrome, but the first symptom that you will see isspleen, and pancreas.
a difficulty in breathing called dyspnea. Dyspnea willTreatments:
cause your cat a very slow but progressive difficultyTreatments for Nephrotic syndrome will all depend on
in breathing. It is also referred to as air hunger, andhow seriously your cat is affected. If they are stable,
as it progresses, your cat will start to pant.they can be treated as outpatients by your
Panting is normal in several breeds of dogs, but yourveterinarian, otherwise they will have to be
cat is not a dog and anytime they pant it shouldhospitalized. The first form of treatment will be
immediately signal you that something is wrong; veryantibiotics to control any type of an infection, but this
wrong. Dyspnea is often associated with a lung orwill quickly be followed by a modification of your cats
heart disease, and with this syndrome, it is the lungsdiet. The will be placed immediately on a low salt and
that ere causing the symptoms.low protein diet to slow the loss of protein in their
The next set of symptoms, which are very difficultsystem.
to actually see, will surface when your cat stopsIf your cat is in any of the stages of kidney failure,
eating almost to the point of being anorexic. Your catthey will need intravenous fluid therapy. If they have
has now developed edema, which is a conditiona large build up of fluid, this will have to be addressed
where a large amount of fluid has developed either inby diuretics to remove the fluid. Your veterinarian
the circulatory system or the tissues between themay also choose to treat this with a very low dose
body's cells. Eating or drinking causes additionalof aspirin, but this is extremely dangerous because of
pressure, and as a result, they simply quite eating.aspirins toxicity in cats and should only be done by
This pressure can affect several organs, includingyour veterinarian.
their eyes, and the final symptom you see may be aSummary:
loss of vision.Nephrotic syndrome in cats can be a very serious
Causes:threat to your cat, but it can also be successfully
There are two distinctive causes of Nephrotictreated if identified early. If you understand the
syndrome; Glomerulonephritis or GN, and Amyloidosis.symptoms and seek treatment as soon as possible,
However, the most common cause is GN.your cat should live a normal life after treatment.
GN is a condition that occurs when the very smallBut there is still one very perplexing problem with this
blood vessels, called the gomeruli in your cat, startssyndrome; there is still no known or documented
to leak. These small capillaries are located in your catsprevention.